Last Word on Point:Counterpoint: Exercise-induced intrapulmonary shunting is imaginary vs. real.
نویسندگان
چکیده
Andrew T. Lovering, Marlowe W. Eldridge, and Michael K. Stickland University of Oregon, Department of Human Physiology, Eugene, Oregon; Department of Population Health Sciences, Department of Pediatrics, and Department of Biomedical Engineering, University of Wisconsin School of Medicine and Public Health, John Rankin Laboratory of Pulmonary Medicine, Madison, Wisconsin; Division of Pulmonary Medicine, Department of Medicine, University of Alberta, and Centre for Lung Health (Covenant Health), Edmonton, Alberta, Canada
منابع مشابه
Point:Counterpoint Comments Comments on Point:Counterpoint: Exercise-induced intrapulmonary shunting is imaginary vs. real IT’S TOO EARLY FOR THE SHUNT DEBATE
TO THE EDITOR: The issue whether shunt does (2) or does not (1) develop during exercise and whether shunt is responsible for the increased A-aDO2 seen in many people during exercise is developing into a methodological debate that will not be solved with the information available at this time. We do not know the in vivo bubble sizes in saline contrast echocardiography nor do we know the influenc...
متن کاملIntrapulmonary shunting and pulmonary gas exchange during normoxic and hypoxic exercise in healthy humans.
Exercise-induced intrapulmonary arteriovenous shunting, as detected by saline contrast echocardiography, has been demonstrated in healthy humans. We have previously suggested that increases in both pulmonary pressures and blood flow associated with exercise are responsible for opening these intrapulmonary arteriovenous pathways. In the present study, we hypothesized that, although cardiac outpu...
متن کاملExercise-induced intrapulmonary arteriovenous shunting in healthy humans.
We hypothesized that increasing exercise intensity recruits dormant arteriovenous intrapulmonary shunts, which may contribute to the widened alveolar-arterial oxygen difference seen with exercise. Twenty-three healthy volunteers (13 men and 10 women, aged 23-48 yr) with normal lung function and a wide range of fitness (mean maximal oxygen uptake = 126% predicted; range = 78-200% predicted) were...
متن کاملIntrapulmonary arteriovenous shunts of 15 m in diameter probably do not contribute to arterial hypoxemia in maximally exercising Thoroughbred horses
Manohar, Murli, and Thomas E. Goetz. Intrapulmonary arteriovenous shunts of 15 m in diameter probably do not contribute to arterial hypoxemia in maximally exercising Thoroughbred horses. J Appl Physiol 99: 224–229, 2005. First published March 17, 2005; doi:10.1152/japplphysiol.01230.2004.—The present study examined whether Thoroughbred horses performing strenuous exercise exhibit intrapulmonary...
متن کاملCounterpoint: Exercise-induced intrapulmonary shunting is real.
intrapulmonary shunt is miniscule is further confirmed by a recent study reporting venous admixture in very fit athletes during exercise breathing pure O 2 (18). During 100% oxygen breathing, alveolar PO 2 is elevated to such an extent that ventilation-perfusion inequality and diffusion limitation no longer contribute to the AaDO 2 —it can be explained only by right to left shunting (18). In th...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Journal of applied physiology
دوره 107 3 شماره
صفحات -
تاریخ انتشار 2009